Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.36 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.36 |
| ▸ | CACNA2D3 | Q8IZS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634012 | 0.93 | PDE4B (0.41) | P2RX3CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL19634031 | 0.89 | STS (0.36) | P2RX3PDE4BMEN1KMT2APIK3CD | |
| SCHEMBL19634176 | 0.89 | P2RX3 (0.36) | P2RX3MEN1KMT2AMAPTSTS | |
| SCHEMBL19634114 | 0.88 | SCN1A (0.37) | P2RX3PDE4BMEN1KMT2APIK3CD | |
| SCHEMBL19613880 | 0.84 | SCN1A (0.41) | P2RX3CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL19634139 | 0.82 | MAPT (0.39) | P2RX3CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL19634096 | 0.79 | MAPT (0.39) | P2RX3CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL19627640 | 0.78 | SCN8A (0.41) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL19613659 | 0.78 | SCN8A (0.46) | PDE4BSCN1ASCN8APDE4APDE4C | |
| SCHEMBL19633926 | 0.77 | STS (0.36) | P2RX3PDE4BMEN1KMT2APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |