Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 11/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 11/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21794018 | 0.72 | SCN1A (0.37) | SCN1ASCN8ASCN5A | |
| SCHEMBL21794010 | 0.69 | SCN1A (0.39) | SCN1ASCN8A | |
| SCHEMBL21783512 | 0.69 | SCN1A (0.32) | SCN1ASCN8ASCN5AMAPT | |
| SCHEMBL21783420 | 0.62 | MAPT (0.35) | SCN1ASCN8ASCN5AMAPT | |
| SCHEMBL25083839 | 0.61 | FFAR2 (0.37) | MAPT | |
| SCHEMBL14547682 | 0.59 | — | — | |
| SCHEMBL30076665 | 0.59 | CES2 (0.37) | MAPT | |
| SCHEMBL9287745 | 0.59 | CES2 (0.37) | MAPT | |
| SCHEMBL21794024 | 0.58 | GRM5 (0.33) | SCN1ASCN8ASCN5A | |
| SCHEMBL21794016 | 0.57 | SMN1; SMN2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |