Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LOX | P28300 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634424 | 0.85 | LOXL2 (0.52) | MCHR1HDAC3HDAC6NCOR2HPGD | |
| SCHEMBL19634682 | 0.84 | KMT2A (0.55) | MCHR1HDAC3HDAC6NCOR2HPGD | |
| SCHEMBL19634404 | 0.81 | LOXL2 (0.64) | MCHR1HDAC3HDAC6NCOR2HPGD | |
| SCHEMBL8404711 | 0.81 | SMN1; SMN2 (0.55) | MCHR1HDAC3HDAC6NCOR2HPGD | |
| SCHEMBL8404664 | 0.79 | HDAC3 (0.61) | MCHR1HDAC3HDAC6NCOR2HPGD | |
| SCHEMBL23568255 | 0.79 | SMN1; SMN2 (0.57) | MCHR1HDAC3HDAC6NCOR2HPGD | |
| SCHEMBL19634455 | 0.79 | HDAC6 (0.59) | HDAC3HDAC6HPGDALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL11907494 | 0.78 | HDAC3 (0.59) | MCHR1HDAC3HDAC6NCOR2HPGD | |
| SCHEMBL23254636 | 0.77 | CYP1A2 (0.68) | MCHR1HDAC3HDAC6NCOR2ALDH1A1 | |
| SCHEMBL24808224 | 0.77 | SMN1; SMN2 (0.54) | MCHR1HDAC3HDAC6NCOR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |