Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LOX | P28300 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634744 | 0.87 | LOXL2 (0.54) | LOXL2ALDH1A1LOXHPGDNPC1 | |
| SCHEMBL19634404 | 0.87 | LOXL2 (0.64) | LOXL2ALDH1A1LOXHPGDMCHR1 | |
| SCHEMBL19634423 | 0.85 | MCHR1 (0.50) | LOXL2ALDH1A1LOXHPGDMCHR1 | |
| SCHEMBL19634450 | 0.84 | HDAC1 (0.54) | ALDH1A1HPGDHDAC3HDAC6KMT2A | |
| SCHEMBL19634682 | 0.83 | KMT2A (0.55) | LOXL2ALDH1A1LOXHPGDMCHR1 | |
| SCHEMBL8404700 | 0.82 | SMN1; SMN2 (0.58) | LOXL2ALDH1A1LOXHPGDMCHR1 | |
| SCHEMBL21016154 | 0.81 | HDAC6 (0.56) | ALDH1A1HPGDHDAC3HDAC6KMT2A | |
| SCHEMBL24808224 | 0.76 | SMN1; SMN2 (0.54) | LOXL2ALDH1A1LOXHPGDMCHR1 | |
| SCHEMBL23568255 | 0.76 | SMN1; SMN2 (0.57) | LOXL2ALDH1A1LOXHPGDMCHR1 | |
| SCHEMBL19634811 | 0.75 | ROCK2 (0.50) | ALDH1A1HPGDHDAC3HDAC6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |