Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LOX | P28300 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404700 | 0.91 | SMN1; SMN2 (0.58) | LOXL2HPGDALDH1A1LOXKMT2A | |
| SCHEMBL19634424 | 0.87 | LOXL2 (0.52) | LOXL2HPGDALDH1A1LOXKMT2A | |
| SCHEMBL19634682 | 0.86 | KMT2A (0.55) | LOXL2HPGDALDH1A1LOXKMT2A | |
| SCHEMBL2056358 | 0.85 | HPGD (0.64) | HPGDALDH1A1KMT2ANAMPTNPC1 | |
| SCHEMBL7445362 | 0.85 | HPGD (0.64) | LOXL2HPGDALDH1A1KMT2ANAMPT | |
| SCHEMBL24808224 | 0.84 | SMN1; SMN2 (0.54) | LOXL2HPGDALDH1A1LOXKMT2A | |
| SCHEMBL19634293 | 0.84 | LOXL2 (0.65) | LOXL2HPGDALDH1A1LOXNPC1 | |
| SCHEMBL23568255 | 0.84 | SMN1; SMN2 (0.57) | LOXL2HPGDALDH1A1LOXKMT2A | |
| SCHEMBL9229365 | 0.83 | ALDH1A1 (0.67) | LOXL2HPGDALDH1A1KMT2ANAMPT | |
| SCHEMBL19465880 | 0.83 | HPGD (0.62) | LOXL2HPGDALDH1A1LOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |