Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471261 | 0.92 | ALDH1A1 (0.44) | ALDH1A1KMT2APOLBMAPTRAB9A | |
| SCHEMBL19634399 | 0.86 | ERCC1 (0.44) | ALDH1A1KMT2APOLBMAPTRAB9A | |
| SCHEMBL21015839 | 0.86 | HDAC6 (0.52) | ALDH1A1POLBHDAC1HDAC3HDAC6 | |
| SCHEMBL23471018 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KMT2APOLBMAPTRAB9A | |
| SCHEMBL23470997 | 0.85 | HDAC3 (0.44) | ALDH1A1KMT2APOLBMAPTRAB9A | |
| SCHEMBL23471262 | 0.85 | KMT2A (0.55) | ALDH1A1KMT2APOLBMAPTRAB9A | |
| SCHEMBL19634448 | 0.84 | KMT2A (0.58) | ALDH1A1KMT2APOLBMAPTRAB9A | |
| SCHEMBL19634683 | 0.82 | HDAC6 (0.42) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL19634692 | 0.80 | KMT2A (0.57) | ALDH1A1KMT2APOLBMAPTRAB9A | |
| SCHEMBL21015786 | 0.79 | HDAC6 (0.45) | ALDH1A1KMT2ARAB9AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |