Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634462 | 0.91 | HDAC1 (0.50) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL19634692 | 0.86 | KMT2A (0.57) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL23471262 | 0.85 | KMT2A (0.55) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL19634445 | 0.84 | ALDH1A1 (0.51) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL23471131 | 0.84 | KMT2A (0.62) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL19634695 | 0.84 | ERCC1 (0.49) | KMT2AHDAC1HDAC6RAB9AHDAC2 | |
| SCHEMBL23471106 | 0.84 | HDAC1 (0.55) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL19634696 | 0.84 | KMT2A (0.54) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL23471107 | 0.82 | KMT2A (0.49) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL11861379 | 0.81 | ALDH1A1 (0.51) | HDAC1HDAC6ALDH1A1RAB9AHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |