Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.57 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.57 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471206 | 1.00 | GNAI3 (0.57) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL793522 | 0.98 | GNAI3 (0.53) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL19865645 | 0.92 | GNAI3 (0.57) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL793883 | 0.91 | GNAI3 (0.45) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL25135123 | 0.91 | GNAI3 (0.45) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL21016223 | 0.90 | GNAI3 (0.47) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL23471324 | 0.90 | GNAI3 (0.47) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL19634476 | 0.88 | GNAI3 (0.44) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL21303867 | 0.88 | GNAI3 (0.52) | GNAI3GNAO1GNAI1LTA4HHTR1A | |
| SCHEMBL21477161 | 0.88 | GNAI3 (0.52) | GNAI3GNAO1GNAI1LTA4HHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |