Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16752076 | 0.81 | ALDH1A1 (0.36) | OPRD1OPRK1 | |
| SCHEMBL16752112 | 0.81 | OPRD1 (0.33) | KISS1ROPRD1OPRK1 | |
| SCHEMBL13397769 | 0.81 | OPRD1 (0.36) | OPRD1OPRK1 | |
| SCHEMBL13995988 | 0.78 | MAOB (0.39) | MAOB | |
| SCHEMBL19634479 | 0.76 | KISS1R (0.34) | KISS1R | |
| SCHEMBL19402489 | 0.74 | — | — | |
| SCHEMBL19402460 | 0.74 | — | — | |
| SCHEMBL19402459 | 0.74 | — | — | |
| SCHEMBL22872239 | 0.72 | — | — | |
| SCHEMBL13397824 | 0.72 | OPRD1 (0.39) | OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |