Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471263 | 0.85 | OPRM1 (0.46) | LOXL2HDAC6HDAC3OPRM1OPRD1 | |
| SCHEMBL19634742 | 0.85 | LOXL2 (0.54) | LOXL2OPRM1OPRD1 | |
| SCHEMBL19634683 | 0.80 | HDAC6 (0.42) | LOXL2HDAC6HDAC3NCOR2HDAC1 | |
| SCHEMBL23471262 | 0.80 | KMT2A (0.55) | HDAC6HDAC3OPRM1OPRD1HDAC1 | |
| SCHEMBL19634427 | 0.80 | HDAC3 (0.48) | LOXL2HDAC6HDAC3NCOR2HDAC1 | |
| SCHEMBL14571402 | 0.79 | OPRM1 (0.53) | HDAC6OPRM1OPRD1HDAC1MLYCD | |
| SCHEMBL19634429 | 0.79 | LOXL2 (0.48) | LOXL2HDAC6HDAC3NCOR2HDAC1 | |
| SCHEMBL19634392 | 0.78 | HPGD (0.58) | LOXL2HDAC6HDAC3NCOR2HDAC1 | |
| SCHEMBL15347843 | 0.77 | HPGD (0.63) | HDAC6HDAC3OPRM1OPRD1HDAC1 | |
| SCHEMBL19634689 | 0.77 | MLYCD (0.54) | LOXL2HDAC6HDAC3NCOR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |