Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.54 |
| ▸ | LOX | P28300 | 4/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634293 | 0.88 | LOXL2 (0.65) | LOXL2LOXHTR2CCFDALDH1A1 | |
| SCHEMBL19634424 | 0.87 | LOXL2 (0.52) | LOXL2LOXALDH1A1HPGDNPC1 | |
| SCHEMBL19634811 | 0.86 | ROCK2 (0.50) | ALDH1A1HPGDSMN1; SMN2MRGPRX4ROCK2 | |
| SCHEMBL19634711 | 0.85 | MEN1 (0.56) | LOXL2LOXHTR2CCFDALDH1A1 | |
| SCHEMBL23471115 | 0.83 | CHRM2 (0.52) | ALDH1A1HPGDSMN1; SMN2MRGPRX4ROCK2 | |
| SCHEMBL21015345 | 0.83 | ROCK2 (0.47) | ALDH1A1HPGDSMN1; SMN2MRGPRX4ROCK2 | |
| SCHEMBL7022389 | 0.78 | LOXL2 (0.54) | LOXL2LOXALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19634726 | 0.78 | LOXL2 (0.63) | LOXL2LOXHTR2CCFDALDH1A1 | |
| SCHEMBL8284791 | 0.76 | HPGD (0.57) | LOXL2LOXALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23471233 | 0.76 | MRGPRX4 (0.60) | LOXL2LOXALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |