Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21015335 | 0.89 | LMNA (0.46) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21015333 | 0.88 | MEN1 (0.49) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21015334 | 0.87 | PARP1 (0.53) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21015332 | 0.87 | PARP1 (0.52) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21016168 | 0.86 | KDM1A (0.53) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21015768 | 0.86 | ALDH1A1 (0.52) | MEN1KMT2ALMNASMN1; SMN2MAPK1 | |
| SCHEMBL21016164 | 0.86 | RAB9A (0.54) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21016169 | 0.85 | HPGD (0.53) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21015218 | 0.84 | LMNA (0.53) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21016172 | 0.83 | RAB9A (0.55) | MEN1KMT2ASMN1; SMN2TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190151403-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. | 2019-05-23 | — | — | US | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151403-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | MALT1, MYLK2, FKBP1B | MEN1 369/4885KMT2A 4599/4885LMNA 3053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.