Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17479406 | 0.73 | HCAR2 (0.40) | MAPTHCAR2 | |
| SCHEMBL19635846 | 0.71 | HCAR2 (0.36) | HCAR2 | |
| SCHEMBL19615335 | 0.70 | MAPT (0.33) | MAPTHPGD | |
| SCHEMBL23663106 | 0.68 | TSHR (0.35) | MAPTHPGD | |
| SCHEMBL29080416 | 0.68 | KDM4E (0.35) | MAPTHPGDTACR1 | |
| SCHEMBL25291229 | 0.66 | — | — | |
| SCHEMBL31245536 | 0.66 | BACE1 (0.33) | MAPTHPGDTACR1 | |
| SCHEMBL21957976 | 0.66 | BACE1 (0.33) | MAPTHPGDTACR1 | |
| SCHEMBL19634979 | 0.65 | KDM4C (0.45) | MAPTHPGDHCAR2 | |
| SCHEMBL9026695 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198341-A1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | WO | disclosed |