Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21957976 | 1.00 | BACE1 (0.33) | BACE1TACR1MAPTTSHRCHRM2 | |
| SCHEMBL21957858 | 0.85 | L3MBTL1 (0.37) | BACE1TACR1MAPTKMT2AKDM4E | |
| SCHEMBL31245546 | 0.78 | KDM4E (0.44) | MAPTTSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL21957880 | 0.78 | KDM4E (0.44) | MAPTTSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL29770728 | 0.78 | KDM4E (0.53) | BACE1TACR1MAPTTSHRCHRM2 | |
| SCHEMBL17986906 | 0.78 | KDM4E (0.53) | BACE1TACR1MAPTTSHRCHRM2 | |
| SCHEMBL8623554 | 0.76 | CHRM2 (0.45) | MAPTTSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL30289758 | 0.76 | KMO (0.38) | BACE1MAPTTSHRKDM4EALOX15 | |
| SCHEMBL16375222 | 0.76 | KMO (0.38) | BACE1MAPTTSHRKDM4EALOX15 | |
| SCHEMBL31132954 | 0.76 | KDM5A (0.35) | BACE1TACR1TSHRCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113316568-B | 2-Formyl-3-hydroxyphenyloxymethyl compounds capable of modulating hemoglobin | 全球血液疗法股份有限公司 | 2024-11-08 | — | — | CN | disclosed |