Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725480 | 0.87 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL28361799 | 0.85 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL3509806 | 0.76 | ADRB2 (0.34) | PRMT5WDR77 | |
| SCHEMBL5700019 | 0.76 | CHRNB2 (0.35) | PRMT5WDR77 | |
| SCHEMBL20691202 | 0.76 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL8065482 | 0.76 | ADRB2 (0.34) | PRMT5WDR77 | |
| SCHEMBL12758856 | 0.76 | CYP11B1 (0.38) | PRMT5WDR77 | |
| SCHEMBL21100843 | 0.76 | PRMT5 (0.31) | PRMT5WDR77 | |
| SCHEMBL24362607 | 0.74 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL798755 | 0.73 | HCAR2 (0.40) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201150-A1 | ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2017-11-23 | — | — | WO | disclosed |