Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.54 |
| ▸ | BTK | Q06187 | 19/20 | 0.49 |
| ▸ | EGFR | P00533 | 8/20 | 0.49 |
| ▸ | SRC | P12931 | 6/20 | 0.49 |
| ▸ | BMX | P51813 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | TEC | P42680 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18700213 | 0.89 | SCN9A (0.53) | SCN4ABTKEGFRSRCBMX | |
| SCHEMBL29536436 | 0.79 | SCN4A (0.53) | SCN4ABTKEGFRSRCBMX | |
| SCHEMBL16197120 | 0.78 | SCN9A (0.50) | SCN4ABTKSRC | |
| SCHEMBL18700125 | 0.78 | BTK (0.50) | BTK | |
| SCHEMBL18700175 | 0.77 | LTA4H (0.48) | BTKEGFRSRC | |
| SCHEMBL18700210 | 0.75 | CHEK2 (0.48) | BTK | |
| SCHEMBL28574332 | 0.73 | BTK (0.69) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL25891793 | 0.73 | GAA (0.43) | BTK | |
| SCHEMBL3135431 | 0.72 | SCN9A (0.72) | SCN4A | |
| SCHEMBL29709430 | 0.72 | LCK (0.45) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198050-A1 | 5-AMINOPYRAZOLE CARBOXAMIDE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | 浙江予川医药科技有限公司 | 2017-11-23 | — | — | WO | disclosed |