⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19636411 | 0.81 | — | — | |
| SCHEMBL18520505 | 0.81 | — | — | |
| SCHEMBL20365542 | 0.80 | ALDH1A1 (0.47) | — | |
| SCHEMBL12458682 | 0.80 | ALDH1A1 (0.31) | — | |
| SCHEMBL25015251 | 0.80 | — | — | |
| SCHEMBL17030121 | 0.79 | — | — | |
| SCHEMBL12091710 | 0.79 | NOS1 (0.31) | — | |
| SCHEMBL17975427 | 0.78 | EPHX1 (0.38) | — | |
| SCHEMBL20754289 | 0.77 | — | — | |
| Guanoctine SCHEMBL5909699 | 0.77 | POLB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230256047-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF MUSCULAR DYSTROPHY | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-08-17 | — | — | US | disclosed |
| EP-2970586-B1 | AMINE FUNCTIONAL POLYAMIDES | GENZYME CORP (US) | 2022-12-07 | — | — | EP | disclosed |
| US-10874752-B2 | MIBG analogs and uses thereof | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200054741-A1 | PEPTIDE-BASED VACCINES, METHODS OF MANUFACTURING, AND USES THEREOF FOR INDUCING AN IMMUNE RESPONSE | AVIDEA TECHNOLOGIES, INC. (US) | 2020-02-20 | — | — | US | disclosed |