Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121704 | 0.81 | CNR1 (0.73) | TDP1L3MBTL1CNR1CNR2ALDH1A1 | |
| SCHEMBL7365613 | 0.79 | CNR2 (0.52) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL28183370 | 0.79 | CNR2 (0.47) | TDP1L3MBTL1CNR1CNR2ALDH1A1 | |
| SCHEMBL19636452 | 0.79 | CNR2 (0.47) | TDP1L3MBTL1CNR1CNR2ALDH1A1 | |
| SCHEMBL9321460 | 0.76 | CNR2 (0.51) | CNR1CNR2ALDH1A1GAA | |
| SCHEMBL25393772 | 0.75 | CNR1 (0.59) | TDP1L3MBTL1CNR1CNR2ALDH1A1 | |
| SCHEMBL30657621 | 0.75 | MEN1 (0.50) | TDP1L3MBTL1CNR1CNR2ALDH1A1 | |
| SCHEMBL19636450 | 0.75 | ALDH1A1 (0.46) | TDP1L3MBTL1CNR1CNR2ALDH1A1 | |
| SCHEMBL5569757 | 0.74 | NR1D1 (0.57) | CNR1CNR2MAPTMEN1KMT2A | |
| SCHEMBL2485275 | 0.74 | SMN1; SMN2 (0.49) | TDP1L3MBTL1CNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197670-A1 | METHOD FOR SYNTHESIZING 1,2-DIMETHYLENE CYCLOBUTANE CHIRAL COMPOUND | 中国科学院福建物质结构研究所 | 2017-11-23 | — | — | WO | disclosed |