SCHEMBL7365613

SCHEMBL7365613

Cc1ccc(S(=O)(=O)N(CCc2cccs2)CC(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.52
CNR1 P21554 1/20 0.52
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5569757 0.84 NR1D1 (0.57) CNR2CNR1MEN1KMT2A
SCHEMBL8607609 0.81 KEAP1 (0.64) CNR2
SCHEMBL22469193 0.81 CNR2 (0.72) CNR2MEN1KMT2A
SCHEMBL6121704 0.80 CNR1 (0.73) CNR2CNR1
SCHEMBL5569737 0.80 CA12 (0.50) CNR2MEN1KMT2A
SCHEMBL8200276 0.80 KEAP1 (0.62) CNR2
SCHEMBL19636449 0.79 TDP1 (0.53) CNR2CNR1MEN1KMT2A
SCHEMBL7961836 0.78 KEAP1 (0.68) CNR2
SCHEMBL5569686 0.78 MEN1 (0.51) MEN1KMT2A
SCHEMBL9321460 0.78 CNR2 (0.51) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1001973-A1 COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 Elan Pharmaceuticals, Inc. (US) 2000-05-24 EP disclosed
WO-1999006433-A1 COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARMACEUTICALS, INC. (US) 1999-02-11 WO disclosed