SCHEMBL19636619

SCHEMBL19636619

CCN(CC)CCNC(=O)c1ccc2cc(NC(N)=O)ccc2n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.48
ALDH1A1 P00352 5/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 2/20 0.47
NFKB1 P19838 1/20 0.47
KCNH2 Q12809 1/20 0.47
POLB P06746 2/20 0.46
BLM P54132 2/20 0.46
CYP3A4 P08684 1/20 0.46
THRB P10828 1/20 0.46
ATM Q13315 1/20 0.46
LMNA P02545 2/20 0.44
SLC22A2 O15244 1/20 0.44
SLC22A1 O15245 1/20 0.44
TSHR P16473 1/20 0.44
ACHE P22303 1/20 0.44
MAPK1 P28482 1/20 0.44
CYP2C19 P33261 1/20 0.44
PMP22 Q01453 1/20 0.43
KMT2A Q03164 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19611848 0.90 TERT (0.49) TERTALDH1A1SMN1; SMN2KDM4ENFKB1
SCHEMBL19632953 0.88 TERT (0.47) TERTALDH1A1SMN1; SMN2KDM4ENFKB1
SCHEMBL20024501 0.88 TERT (0.47) TERTALDH1A1SMN1; SMN2KDM4ENFKB1
SCHEMBL25963271 0.84 TERT (0.44) TERTALDH1A1SMN1; SMN2KDM4ENFKB1
SCHEMBL16260991 0.84 TERT (0.44) TERTALDH1A1SMN1; SMN2KDM4ENFKB1
SCHEMBL22754787 0.84 TERT (0.47) TERTALDH1A1SMN1; SMN2KDM4ENFKB1
SCHEMBL29472460 0.83 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2KDM4ENFKB1KCNH2
SCHEMBL15840356 0.83 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2KDM4ENFKB1KCNH2
SCHEMBL14310903 0.82 ACKR3 (0.53) ALDH1A1SMN1; SMN2KDM4ENFKB1BLM
SCHEMBL25963520 0.81 TERT (0.42) TERTALDH1A1SMN1; SMN2KDM4ENFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11747310-B2 Methods for liquid chromatography calibration for rapid labeled N-glycans WATERS TECHNOLOGIES CORPORATION (US) 2023-09-05 US disclosed
US-11371996-B2 Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same WATERS TECHNOLOGIES CORPORATION (US) 2022-06-28 US disclosed
US-20200124574-A1 METHODS FOR LIQUID CHROMATOGRAPHY CALIBRATION FOR RAPID LABELED N-GLYCANS WATERS TECHNOLOGIES CORPORATION 2020-04-23 US disclosed
US-20180188259-A1 METHODS FOR THE RAPID PREPARATION OF LABELED GLYCOSYLAMINES AND FOR THE ANALYSIS OF GLYCOSYLATED BIOMOLECULES PRODUCING THE SAME WATERS TECHNOLOGIES CORPORATION (US) 2018-07-05 US disclosed
US-20170336368-A1 METHODS FOR LIQUID CHROMATOGRAPHY CALIBRATION FOR RAPID LABELED N-GLYCANS WATERS TECHNOLOGIES CORPORATION (US) 2017-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170336368-A1 METHODS FOR LIQUID CHROMATOGRAPHY CALIBRATION FOR RAPID LABELED N-GLYCANS DDOST, STT3B, CSGALNACT1 TERT 4240/4885ALDH1A1 1045/4885SMN1; SMN2 4368/4885
US-20200124574-A1 METHODS FOR LIQUID CHROMATOGRAPHY CALIBRATION FOR RAPID LABELED N-GLYCANS DDOST, STT3B, CSGALNACT1 TERT 4240/4885ALDH1A1 1045/4885SMN1; SMN2 4368/4885
US-11747310-B2 Methods for liquid chromatography calibration for rapid labeled N-glycans DDOST, STT3B, CSGALNACT1 TERT 4240/4885ALDH1A1 1045/4885SMN1; SMN2 4368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.