SCHEMBL9705223

SCHEMBL9705223

CCCCCCN(CCCCCC)CCOCCN(CCCCCC)CCCCCC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.46
THRB P10828 2/20 0.43
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 1/20 0.43
TSHR P16473 2/20 0.40
KDM5A P29375 2/20 0.38
PHF8 Q9UPP1 2/20 0.38
KDM4C Q9H3R0 1/20 0.38
KCNH2 Q12809 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19637028 0.95 MEN1 (0.50) DNM1THRBMEN1HTTKMT2A
SCHEMBL27445853 0.95 DNM1 (0.42) DNM1THRBMEN1HTTKMT2A
SCHEMBL9705221 0.93 DNM1 (0.39) DNM1THRBMEN1HTTKMT2A
SCHEMBL28972955 0.91 DNM1 (0.56) DNM1THRBMEN1HTTKMT2A
SCHEMBL26800576 0.91 DNM1 (0.42) DNM1THRBMEN1HTTKMT2A
SCHEMBL9069944 0.91 DNM1 (0.42) DNM1THRBMEN1HTTKMT2A
SCHEMBL7695726 0.91 DNM1 (0.42) DNM1THRBMEN1HTTKMT2A
SCHEMBL10422513 0.90 HTT (0.54) DNM1THRBMEN1HTTKMT2A
SCHEMBL9549348 0.90 HTT (0.54) DNM1THRBMEN1HTTKMT2A
SCHEMBL12120261 0.90 HTT (0.54) DNM1THRBMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0214852-B1 PERFLUOROAMINOETHERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-28 EP disclosed
US-5049670-A Pour point MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-17 US disclosed
US-4929725-A NONFLAMMABLE, HYDRAULIC FLUIDS MOORE GEORGE G I (US) 1990-05-29 US disclosed
US-4788339-A HIGH BOILING, LOW POUR POINT; HYDRAULIC FLUIDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-29 US disclosed
EP-0214852-A2 Perfluoroaminoethers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-03-18 EP disclosed