Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | ACP1 | P24666 | 2/20 | 0.31 |
| ▸ | IL1RN | P18510 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24977490 | 0.77 | KEAP1 (0.48) | KEAP1CA12CA9HDAC3HDAC4 | |
| SCHEMBL23958391 | 0.66 | KEAP1 (0.43) | KEAP1CA12CA9HDAC3HDAC4 | |
| SCHEMBL28185649 | 0.64 | CES1 (0.39) | MEN1KMT2ALMNAHPGDKDM4E | |
| SCHEMBL29092698 | 0.63 | KEAP1 (0.56) | KEAP1CA12CA9HDAC1CA1 | |
| SCHEMBL9231787 | 0.63 | KEAP1 (0.56) | KEAP1CA12CA9CA1CA2 | |
| SCHEMBL18898459 | 0.63 | SMN1; SMN2 (0.49) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL10766214 | 0.63 | KEAP1 (0.54) | KEAP1CA12CA9HDAC3HDAC4 | |
| SCHEMBL24841605 | 0.62 | ACP1 (0.51) | CA12CA9CA1CA2ACP1 | |
| SCHEMBL21283388 | 0.62 | CA12 (0.60) | KEAP1CA12CA9HDAC3HDAC4 | |
| SCHEMBL29071610 | 0.62 | KEAP1 (0.44) | KEAP1CA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017199264-A1 | NOVEL PROCESS FOR THE PREPARATION OF BELINOSTAT | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2017-11-23 | — | — | WO | disclosed |