Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | IL1RN | P18510 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20623069 | 0.87 | KEAP1 (0.39) | KEAP1CA1CA2IL1RNERAP1 | |
| SCHEMBL21504863 | 0.83 | SMN1; SMN2 (0.46) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL24977490 | 0.83 | KEAP1 (0.48) | KEAP1CA1CA2IL1RNERAP1 | |
| SCHEMBL18466103 | 0.77 | ALDH1A1 (0.44) | CA1CA2KMT2AMEN1PKM | |
| SCHEMBL18763270 | 0.73 | — | — | |
| SCHEMBL22669673 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9231787 | 0.71 | KEAP1 (0.56) | KEAP1CA1CA2IL1RNERAP1 | |
| SCHEMBL23797104 | 0.71 | SMN1; SMN2 (0.43) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL25788337 | 0.71 | — | — | |
| SCHEMBL22519836 | 0.70 | EPHX2 (0.37) | CA1CA2CA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11660294-B2 | Compounds, compositions, and methods for the treatment and prevention of avian pathogenic E. coli (APEC) | OHIO STATE INNOVATION FOUNDATION (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210330655-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT AND PREVENTION OF AVIAN PATHOGENIC E. COLI (APEC) | OHIO STATE INNOVATION FOUNDATION | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11660294-B2 | Compounds, compositions, and methods for the treatment and prevention of avian pathogenic E. coli (APEC) | FABP2, APC, AP1G1 | KEAP1 804/4885CA1 1525/4885CA2 2835/4885 |
| US-20210330655-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT AND PREVENTION OF AVIAN PATHOGENIC E. COLI (APEC) | FABP2, APC, AP1G1 | KEAP1 804/4885CA1 1525/4885CA2 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.