Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958391 | 0.83 | KEAP1 (0.43) | KEAP1CA1CA2IL1RNERAP1 | |
| SCHEMBL18898459 | 0.80 | SMN1; SMN2 (0.49) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL19860952 | 0.77 | CYP2C9 (0.49) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL19637798 | 0.77 | KEAP1 (0.35) | KEAP1CA1CA2IL1RNERAP1 | |
| SCHEMBL9231787 | 0.76 | KEAP1 (0.56) | KEAP1CA1CA2IL1RNERAP1 | |
| SCHEMBL19670693 | 0.73 | ALDH1A1 (0.49) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL29092698 | 0.72 | KEAP1 (0.56) | KEAP1CA1CA2IL1RNERAP1 | |
| SCHEMBL10766214 | 0.71 | KEAP1 (0.54) | KEAP1CA1CA2IL1RNERAP1 | |
| SCHEMBL7446297 | 0.70 | KEAP1 (0.58) | KEAP1CA1CA2IL1RNERAP1 | |
| SCHEMBL20636072 | 0.69 | SMN1; SMN2 (0.46) | CA1CA2CA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122929-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2023-01-25 | — | — | EP | disclosed |