Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.61 |
| ▸ | CES1 | P23141 | 3/20 | 0.61 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29746067 | 1.00 | CES2 (0.61) | CES2CES1ACKR3HSP90AB1L3MBTL1 | |
| SCHEMBL6944180 | 0.85 | CES2 (0.57) | CES2CES1ACKR3 | |
| SCHEMBL31130589 | 0.84 | CES2 (0.61) | CES2CES1HSP90AB1L3MBTL1KCNH2 | |
| SCHEMBL954719 | 0.84 | CES2 (0.61) | CES2CES1HSP90AB1L3MBTL1KCNH2 | |
| SCHEMBL3408482 | 0.83 | MAOB (0.46) | CES2CES1ACKR3KCNH2 | |
| SCHEMBL12780437 | 0.82 | HSP90AB1 (0.47) | CES2CES1HSP90AB1L3MBTL1KCNH2 | |
| SCHEMBL29368949 | 0.82 | HSP90AB1 (0.67) | CES2CES1HSP90AB1PKMKCNH2 | |
| SCHEMBL177181 | 0.82 | HSP90AB1 (0.67) | CES2HSP90AB1 | |
| SCHEMBL30494600 | 0.82 | HSP90AB1 (0.47) | CES2CES1HSP90AB1KCNH2 | |
| SCHEMBL9720605 | 0.82 | HSP90AB1 (0.47) | CES2CES1HSP90AB1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801550-A | Novel benzopyran kinase modulators | 理森制药股份公司 | 2016-07-27 | — | — | CN | claimed |
| WO-2015150947-A1 | A PROCESS FOR THE PREPARATION OF ISAVUCONAZOLE AND ITS INTERMEDIATES | WOCKHARDT LIMITED (IN) | 2015-10-08 | — | — | WO | claimed |
| US-5426233-A | Contacting dihalophenone type compound with chiral hydroxylating compound at low temperature | SCHERING CORPORATION (US) | 1995-06-20 | — | — | US | claimed |
| WO-1992017433-A1 | PREPARATION OF CHIRAL HYDROXYKETONES | SCHERING CORPORATION (US) | 1992-10-15 | — | — | WO | claimed |
| EP-0506341-A1 | Preparation of chiral hydroxyketones | SCHERING CORPORATION (US) | 1992-09-30 | — | — | EP | claimed |
| US-20240059677-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | CEREVANCE LTD (GB) | 2024-02-22 | — | — | US | disclosed |
| US-20240043593-A1 | Fluorine-Containing Polymer | CENTRAL GLASS COMPANY, LIMITED (JP) | 2024-02-08 | — | — | US | disclosed |
| CN-116848162-A | Fluorine-containing polymer | 中央硝子株式会社 | 2023-10-03 | — | — | CN | disclosed |
| EP-4211118-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | Cerevance, Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| US-11407732-B1 | Tricyclic degraders of Ikaros and Aiolos | C4 THERAPEUTICS, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| WO-2022053823-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | Cerevance, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |
| CN-105801550-B | Novel chromene kinase modulator | 理森制药股份公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-1112113-A | Novel triazole compound and production process and use thereof | NIHON NOHYAKU CO LTD (JP) | 1995-11-22 | — | — | CN | disclosed |
| EP-0679647-A1 | Novel antifungal triazole compound and production and use thereof | NIHON NOHYAKU CO., LTD. (JP) | 1995-11-02 | — | — | EP | disclosed |
| US-5426233-A | Contacting dihalophenone type compound with chiral hydroxylating compound at low temperature | SCHERING CORPORATION (US) | 1995-06-20 | — | — | US | disclosed |
| US-5405861-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, CO., LTD. (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0613890-A1 | Novel triazole compound, process for preparing the same and antifungal agent containing the same | NIHON NOHYAKU CO., LTD. (JP) | 1994-09-07 | — | — | EP | disclosed |
| WO-1992017433-A1 | PREPARATION OF CHIRAL HYDROXYKETONES | SCHERING CORPORATION (US) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506341-A1 | Preparation of chiral hydroxyketones | SCHERING CORPORATION (US) | 1992-09-30 | — | — | EP | disclosed |
| EP-0421210-A2 | Triazole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059677-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | CHRNA6, CHRM2, CHRNA1 | CES2 208/4885CES1 90/4885ACKR3 733/4885 |
| US-11407732-B1 | Tricyclic degraders of Ikaros and Aiolos | CRBN, IKZF1, IKZF3 | CES2 2962/4885CES1 2610/4885ACKR3 3753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.