Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196379 | 0.83 | CES2 (0.61) | CES2CES1KCNH2ACKR3 | |
| SCHEMBL29746067 | 0.83 | CES2 (0.61) | CES2CES1KCNH2ACKR3 | |
| SCHEMBL29993560 | 0.80 | KCNH2 (0.49) | MAOBMAOAKCNH2CYP11B1CYP11B2 | |
| SCHEMBL8022080 | 0.80 | KCNH2 (0.49) | MAOBMAOAKCNH2CYP11B1CYP11B2 | |
| Hydrazine SCHEMBL8175050 | 0.76 | RAB9A (0.44) | MAOBNPC1RAB9AMAOACES2 | |
| SCHEMBL5255602 | 0.74 | MAOB (0.52) | MAOBMAOAKCNH2CYP11B1CYP11B2 | |
| SCHEMBL9536908 | 0.74 | LMNA (0.52) | MAOBNPC1MEN1MAPTKMT2A | |
| SCHEMBL9423079 | 0.74 | HPGD (0.49) | NPC1RAB9ACES2CES1KCNH2 | |
| SCHEMBL954719 | 0.73 | CES2 (0.61) | CES2CES1KCNH2MDM2MEN1 | |
| SCHEMBL31130589 | 0.73 | CES2 (0.61) | CES2CES1KCNH2MDM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213638-A1 | Method for the asymmetric hydrogenation of olefins utilising photoisomerisation | DSM IP Assets B.V. (NL) | 2010-08-04 | — | — | EP | disclosed |