Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296940 | 0.92 | APP (0.64) | APPNPSR1AKR1B10AKR1B1PKM | |
| SCHEMBL8296939 | 0.92 | APP (0.64) | APPNPSR1AKR1B10AKR1B1PKM | |
| SCHEMBL31030969 | 0.88 | TTR (0.60) | APPNPSR1ALOX5AKR1B10AKR1B1 | |
| SCHEMBL1177761 | 0.88 | TTR (0.60) | APPNPSR1ALOX5AKR1B10AKR1B1 | |
| SCHEMBL1177764 | 0.88 | TTR (0.60) | APPNPSR1ALOX5AKR1B10AKR1B1 | |
| Hydrochloric Acid SCHEMBL10463632 | 0.87 | TTR (0.58) | APPNPSR1ALOX5AKR1B10AKR1B1 | |
| Hydrochloric Acid SCHEMBL10463631 | 0.87 | TTR (0.58) | APPNPSR1ALOX5AKR1B10AKR1B1 | |
| SCHEMBL20358049 | 0.84 | APP (0.63) | APPALOX5AKR1B10AKR1B1TTR | |
| SCHEMBL20358047 | 0.84 | APP (0.63) | APPALOX5AKR1B10AKR1B1TTR | |
| SCHEMBL19244191 | 0.82 | APP (0.60) | APPALOX5PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017199264-A1 | NOVEL PROCESS FOR THE PREPARATION OF BELINOSTAT | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2017-11-23 | — | — | WO | disclosed |