SCHEMBL1177761

SCHEMBL1177761

CCOC(=O)/C=C/c1cccc(N)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 1/20 0.60
▸ DPP4 P27487 1/20 0.60
▸ NPSR1 Q6W5P4 1/20 0.59
▸ CA12 O43570 1/20 0.56
▸ CA1 P00915 1/20 0.56
▸ CA2 P00918 1/20 0.56
▸ CA7 P43166 1/20 0.56
▸ CA9 Q16790 1/20 0.56
▸ CA14 Q9ULX7 1/20 0.56
▸ MAOB P27338 2/20 0.55
▸ BACE1 P56817 2/20 0.54
▸ CYP3A4 P08684 1/20 0.54
▸ FDPS P14324 1/20 0.52
▸ PKM P14618 1/20 0.51
▸ NPC1 O15118 2/20 0.50
▸ RAB9A P51151 2/20 0.50
▸ ALOX5 P09917 1/20 0.50
▸ CASP3 P42574 1/20 0.50
▸ SENP8 Q96LD8 1/20 0.50
▸ SENP7 Q9BQF6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1177764 1.00 TTR (0.60) TTRDPP4NPSR1CA12CA1
SCHEMBL31030969 1.00 TTR (0.60) TTRDPP4NPSR1CA12CA1
Hydrochloric Acid SCHEMBL10463631 0.98 TTR (0.58) TTRDPP4NPSR1CA12CA1
Hydrochloric Acid SCHEMBL10463632 0.98 TTR (0.58) TTRDPP4NPSR1CA12CA1
SCHEMBL9775637 0.91 NPSR1 (0.54) TTRDPP4NPSR1CA12CA1
SCHEMBL4427602 0.89 TTR (0.69) TTRDPP4CA12CA1CA2
SCHEMBL4427604 0.89 TTR (0.69) TTRDPP4CA12CA1CA2
SCHEMBL19637918 0.88 APP (0.62) TTRDPP4NPSR1BACE1PKM
SCHEMBL8296940 0.86 APP (0.64) NPSR1PKMAKR1B10AKR1B1APP
SCHEMBL8296939 0.86 APP (0.64) NPSR1PKMAKR1B10AKR1B1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095297-A Composition for forming cured film, alignment material, and phase difference material — 2026-05-26 — — CN disclosed
WO-2025088969-A1 COMPOSITION FOR FORMING CURED FILM, CURED FILM, ALIGNMENT MATERIAL, AND RETARDATION MATERIAL 日産化学株式会社 2025-05-01 — — WO disclosed
WO-2025023309-A1 COMPOSITION FOR FORMING CURED FILM, ALIGNMENT MATERIAL, AND PHASE-DIFFERENCE MATERIAL 日産化学株式会社 2025-01-30 — — WO disclosed
CN-113874470-B Composition for forming cured film, alignment member, and phase difference member 日产化学株式会社 2024-11-19 — — CN disclosed
WO-2023204281-A1 RESIN COMPOSITION FOR THERMOSETTING PHOTO-ALIGNMENT FILMS 日産化学株式会社 2023-10-26 — — WO disclosed
WO-2023204280-A1 CURED FILM-FORMING COMPOSITION, ALIGNMENT MATERIAL, AND RETARDATION MATERIAL 日産化学株式会社 2023-10-26 — — WO disclosed
WO-2023157934-A1 RESIN COMPOSITION FOR THERMOSETTING PHOTO-ALIGNMENT FILMS 日産化学株式会社 2023-08-24 — — WO disclosed
WO-2022086892-A1 INTERLEUKIN 4 (IL4)-INDUCED GENE 1 INHIBITORS AND METHODS OF USE THEREOF CALITHERA BIOSCIENCES, INC. (US) 2022-04-28 — — WO disclosed
CN-110408159-B Composition for forming cured film, alignment material, and phase difference material 日产化学工业株式会社 2022-02-08 — — CN disclosed
CN-113874470-A Composition for forming cured film, alignment member, and phase difference member 日产化学株式会社 2021-12-31 — — CN disclosed
EP-0894084-B1 CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS SEARLE & CO (US) 2002-06-26 — — EP disclosed
EP-0894084-A1 CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS G.D. SEARLE & CO. (US) 1999-02-03 — — EP disclosed
US-5852210-A Cinnamic acid derivatives G. D. SEARLE & CO. (US) 1998-12-22 — — US disclosed
WO-1997036860-A1 CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS G.D. SEARLE & CO. (US) 1997-10-09 — — WO disclosed
EP-0134337-B1 SUBSTITUTED 2,2-DIMETHYL-5-PHENOXYPENTANOIC ACID BENZAMIDES AND THEIR PRODUCTION WARNER-LAMBERT COMPANY (US) 1988-01-07 — — EP disclosed
US-4554282-A Substituted 2,2-dimethyl-5-phenoxypentanoic acid benzamides as anti-arteriosclerotic agents and method WARNER-LAMBERT COMPANY (US) 1985-11-19 — — US disclosed
EP-0134337-A1 Substituted 2,2-dimethyl-5-phenoxypentanoic acid benzamides and their production WARNER-LAMBERT COMPANY (US) 1985-03-20 — — EP disclosed
US-4413011-A Substituted 2,2-dimethyl-5-phenoxypentanoic acid benzamides as anti-arteriosclerotic agents and method WARNER-LAMBERT COMPANY (US) 1983-11-01 — — US disclosed
US-4094636-A DIAZOTIZATION HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-13 — — US disclosed
US-4051177-A PROCESS FOR THE PREPARATION OF UNSATURATED AMINO COMPOUNDS BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 — — US disclosed
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