Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | BACE1 | P56817 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177764 | 1.00 | TTR (0.60) | TTRDPP4NPSR1CA12CA1 | |
| SCHEMBL1177761 | 1.00 | TTR (0.60) | TTRDPP4NPSR1CA12CA1 | |
| Hydrochloric Acid SCHEMBL10463631 | 0.98 | TTR (0.58) | TTRDPP4NPSR1CA12CA1 | |
| Hydrochloric Acid SCHEMBL10463632 | 0.98 | TTR (0.58) | TTRDPP4NPSR1CA12CA1 | |
| SCHEMBL9775637 | 0.91 | NPSR1 (0.54) | TTRDPP4NPSR1CA12CA1 | |
| SCHEMBL4427602 | 0.89 | TTR (0.69) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4427604 | 0.89 | TTR (0.69) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL19637918 | 0.88 | APP (0.62) | TTRDPP4NPSR1BACE1PKM | |
| SCHEMBL8296940 | 0.86 | APP (0.64) | NPSR1PKMAKR1B10AKR1B1APP | |
| SCHEMBL8296939 | 0.86 | APP (0.64) | NPSR1PKMAKR1B10AKR1B1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239917-A | HDACs inhibitor and preparation method and application thereof | 山东大学 | 2024-06-25 | — | — | CN | disclosed |