SCHEMBL19638028

SCHEMBL19638028

O=C(Nc1cccc(C(F)(F)F)c1)C(Cl)(Cl)Cl

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.64
KMT2A Q03164 5/20 0.64
MEN1 O00255 4/20 0.64
HTT P42858 2/20 0.64
RAB9A P51151 1/20 0.64
ALDH1A1 P00352 6/20 0.62
TP53 P04637 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
NPSR1 Q6W5P4 3/20 0.59
GAA P10253 2/20 0.59
XBP1 P17861 1/20 0.59
LMNA P02545 2/20 0.58
PKM P14618 2/20 0.58
HSP90AA1 P07900 1/20 0.58
KDR P35968 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
CNR2 P34972 1/20 0.56
P2RX1 P51575 1/20 0.56
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2883710 0.86 MAPT (0.68) MAPTKMT2AMEN1HTTRAB9A
SCHEMBL28686536 0.86 MAPT (0.54) MAPTKMT2AMEN1HTTRAB9A
SCHEMBL11584084 0.86 MAPT (0.68) MAPTKMT2AMEN1HTTRAB9A
SCHEMBL11786918 0.84 MAPT (0.57) MAPTKMT2AMEN1HTTRAB9A
SCHEMBL23060422 0.83 MAPT (0.64) MAPTKMT2AMEN1HTTRAB9A
SCHEMBL30977683 0.83 TP53 (0.65) MAPTKMT2AMEN1HTTRAB9A
SCHEMBL4455493 0.83 TP53 (0.65) MAPTKMT2AMEN1HTTRAB9A
SCHEMBL20560345 0.83 MAPT (0.68) MAPTKMT2AMEN1HTTRAB9A
SCHEMBL5597699 0.82 KMT2A (0.90) MAPTKMT2AMEN1HTTRAB9A
SCHEMBL30101230 0.82 KMT2A (0.90) MAPTKMT2AMEN1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623942-B2 Method for extracting salts and temperature- regenerated extracting composition ADIONICS (FR) 2026-05-12 US disclosed
CN-113292128-B Apparatus and method for desalting water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2024-07-05 CN disclosed
US-20230382775-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION ADIONICS (FR) 2023-11-30 US disclosed
US-11772997-B2 Method for extracting salts and temperature-regenerated extracting composition ADIONICS (FR) 2023-10-03 US disclosed
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2023-08-22 US disclosed
CN-109641160-B Method for extracting salt and temperature-regenerated extraction composition 艾迪奥尼克斯公司 2022-02-25 CN disclosed
EP-3247677-B1 LIQUID ORGANIC COMPOSITION FOR ION EXTRACTION IN LIQUID PHASE ADIONICS (FR) 2021-12-08 EP disclosed
US-20210355076-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2021-11-18 US disclosed
CN-113292128-A Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2021-08-24 CN disclosed
US-11066356-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2021-07-20 US disclosed
US-20210214254-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION ADIONICS (FR) 2021-07-15 US disclosed
CN-107207288-B Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2021-07-06 CN disclosed
EP-3808425-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2021-04-21 EP disclosed
EP-3487597-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION Adionics (FR) 2019-05-29 EP disclosed
CN-109641160-A Extract the method for salt and the extracts composition of temperature regeneration 艾迪奥尼克斯公司 2019-04-16 CN disclosed
US-20180009738-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2018-01-11 US disclosed
EP-3247677-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2017-11-29 EP disclosed
CN-107207288-A Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2017-09-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 MAPT 3644/4885KMT2A 4343/4885MEN1 4431/4885
US-20210355076-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID AQP3, AQP1, AQP4 MAPT 3644/4885KMT2A 4343/4885MEN1 4431/4885
US-12623942-B2 Method for extracting salts and temperature- regenerated extracting composition POLQ, NONO, AQP3 MAPT 3057/4885KMT2A 2402/4885MEN1 4052/4885
US-20180009738-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID AQP3, AQP1, AQP4 MAPT 3644/4885KMT2A 4343/4885MEN1 4431/4885
US-11066356-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 MAPT 3644/4885KMT2A 4343/4885MEN1 4431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.