⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154171 | 0.87 | ALDH1A1 (0.33) | — | |
| SCHEMBL15160716 | 0.87 | — | — | |
| SCHEMBL2155471 | 0.84 | ALDH1A1 (0.38) | — | |
| SCHEMBL597712 | 0.82 | — | — | |
| SCHEMBL14671534 | 0.82 | — | — | |
| SCHEMBL23730626 | 0.82 | — | — | |
| SCHEMBL6216216 | 0.82 | — | — | |
| SCHEMBL992402 | 0.82 | — | — | |
| SCHEMBL25004733 | 0.82 | — | — | |
| SCHEMBL642970 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11031626-B2 | Electrolytic solution and electrochemical device containing the same | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2021-06-08 | — | — | US | disclosed |
| US-20200099101-A1 | ELECTROLYTIC SOLUTION AND ELECTROCHEMICAL DEVICE CONTAINING THE SAME | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2020-03-26 | — | — | US | disclosed |
| EP-3191441-B1 | NOVEL PROCESS FOR PREPARATION OF SPIRO[2.5]OCTANE-5,7-DIONE AND SPIRO[3.5]NONANE-6,8-DIONE | BOEHRINGER INGELHEIM INT TRADING SHANGHAI CO LTD (CN) | 2020-02-19 | — | — | EP | disclosed |
| EP-2880008-B1 | PROCESS FOR PREPARING SPIRO[2.5]OCTANE-5,7-DIONE | BOEHRINGER INGELHEIM INT (DE) | 2019-05-29 | — | — | EP | disclosed |
| EP-2880008-B1 | PROCESS FOR PREPARING SPIRO[2.5]OCTANE-5,7-DIONE | BOEHRINGER INGELHEIM INT (DE) | 2019-05-29 | — | — | EP | disclosed |
| US-9212120-B2 | Process for preparing spiro[2.5]octane-5,7-dione | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-12-15 | — | — | US | disclosed |
| US-9212120-B2 | Process for preparing spiro[2.5]octane-5,7-dione | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-12-15 | — | — | US | disclosed |
| US-9212120-B2 | Process for preparing spiro[2.5]octane-5,7-dione | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-12-15 | — | — | US | disclosed |
| EP-2880008-A1 | PROCESS FOR PREPARING SPIRO[2.5]OCTANE-5,7-DIONE | Boehringer Ingelheim International GmbH (DE) | 2015-06-10 | — | — | EP | disclosed |
| US-20140336405-A1 | Process for preparing spiro[2.5]octane-5,7-dione | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
| WO-2008058118-A2 | PREPARATION OF MONTELUKAST AND ITS SALTS | DR. REDDY'S LABORTORIES, LTD. (IN) | 2008-05-15 | — | — | WO | disclosed |
| WO-2006018284-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS CATHEPSIN S INHIBITORS | NOVARTIS AG (CH) | 2006-02-23 | — | — | WO | disclosed |
| EP-0870763-B1 | Condensed piperidine derivatives used as a nitrogen monoxide synthase inhibitors | ONO PHARMACEUTICAL CO (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-6228866-B1 | ADMINISTERING NITRIC OXIDE SYNTHASE INHIBITOR TO TREAT CANCER AND NERVOUS SYSTEM, BRAIN, KIDNEY, RESPIRATORY SYSTEM, AUTOIMMUNES, SKIN AND MUSCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| US-6110930-A | NITRIC OXIDE SYNTHASE INHIBITOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0870763-A1 | Condensed piperidine derivatives used as a nitrogen monoxide synthase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |
| EP-0442820-B1 | Benzimidazole and azabenzimidazole derivatives, thromboxane receptor antagonists, processes for their preparation, synthesis intermediates, compositions containing them | UNION PHARMA SCIENT APPL (FR) | 1995-09-13 | — | — | EP | disclosed |
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |
| EP-0442820-A1 | Benzimidazole and azabenzimidazole derivatives, thromboxane receptor antagonists, processes for their preparation, synthesis intermediates, compositions containing them | LABORATOIRES UPSA (FR) | 1991-08-21 | — | — | EP | disclosed |