SCHEMBL992402

SCHEMBL992402

N#CCC1(CS)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1963806 0.82
SCHEMBL597712 0.72
SCHEMBL14671534 0.72
SCHEMBL6216216 0.72
SCHEMBL23730626 0.72
SCHEMBL25004733 0.72
SCHEMBL642970 0.72
SCHEMBL2154171 0.71 ALDH1A1 (0.33)
SCHEMBL15160716 0.71
Hydrochloric Acid SCHEMBL23703586 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116332816-A Method for preparing 1-mercaptomethyl cyclopropylacetic acid by one-step method 江苏阿尔法药业股份有限公司 2023-06-27 CN claimed
EP-1968943-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LAB LTD (IN) 2013-01-23 EP claimed
EP-2094665-A2 PREPARATION OF MONTELUKAST AND ITS SALTS Dr. Reddy's Laboratories Ltd. (IN) 2009-09-02 EP claimed
US-20090171092-A1 Process for the Preparation of Montelukast and Its Pharmaceutically Acceptable Salts MSN LABORATORIES LIMITED (IN) 2009-07-02 US claimed
WO-2008058118-A2 PREPARATION OF MONTELUKAST AND ITS SALTS DR. REDDY'S LABORTORIES, LTD. (IN) 2008-05-15 WO claimed
CN-114702416-B Method for efficiently preparing montelukast sodium side chain intermediate 重庆普佑生物医药有限公司 2024-07-05 CN disclosed
US-20230279015-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2023-09-07 US disclosed
CN-116332816-A Method for preparing 1-mercaptomethyl cyclopropylacetic acid by one-step method 江苏阿尔法药业股份有限公司 2023-06-27 CN disclosed
CN-114702416-A Method for efficiently preparing montelukast sodium side chain intermediate 法姆瑞斯医药科技(北京)有限公司 2022-07-05 CN disclosed
EP-1968943-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LAB LTD (IN) 2013-01-23 EP disclosed
EP-1968943-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LAB LTD (IN) 2013-01-23 EP disclosed
EP-1948611-B1 Process for the preparation of a leukotriene antagonist and intermediates thereof ESTEVE QUIMICA SA (ES) 2012-05-23 EP disclosed
US-6320052-B1 CRYSTALLINE PRECURSORS OF 1-(((1(R)-(3-(2-(7-CHLORO-2-QUINO LYNYL)ETHENYL)PHENYL)-3-(2-HYDROXY-1-METHYL-ETHYL)PHENYL) PROPYL)THIO)METHYL)CYCLOPROPYLACETIC ACID MERCK & CO., INC. 2001-11-20 US disclosed
EP-0737186-B1 PROCESS FOR THE PREPARATION OF LEUKOTRIENE ANTAGONISTS MERCK & CO INC (US) 1998-08-19 EP disclosed
EP-0805808-A1 PROCESS FOR THE PREPARATION OF 1-(THIOMETHYL)-CYCLOPROPANEACETIC ACID Merck & Co., Inc. (US) 1997-11-12 EP disclosed
US-5614632-A Process for the preparation of leukotriene anatgonists MERCK & CO., INC. (US) 1997-03-25 US disclosed
EP-0737186-A1 PROCESS FOR THE PREPARATION OF LEUKOTRIENE ANTAGONISTS MERCK & CO. INC. (US) 1996-10-16 EP disclosed
WO-1996022987-A1 PROCESS FOR THE PREPARATION OF 1-(THIOMETHYL)-CYCLOPROPANEACETIC ACID MERCK & CO., INC. (US) 1996-08-01 WO disclosed
US-5523477-A REACTING 1,1-CYCLOPROPANEDIMETHANOL WITH DIALKYL SULFITE IN PRESENCE OF ACID OR BASE TO FORM CYCLIC SULFITE, REMOVING ALCOHOL REACTION BY-PRODUCT MERCK & CO., INC. (US) 1996-06-04 US disclosed
WO-1995018107-A1 PROCESS FOR THE PREPARATION OF LEUKOTRIENE ANTAGONISTS MERCK & CO., INC. (US) 1995-07-06 WO disclosed