SCHEMBL1963952

SCHEMBL1963952

O=C(O)c1cccc(Nc2ccccc2)c1C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.68
PBRM1 Q86U86 1/20 0.58
MAPT P10636 4/20 0.54
ALOX15 P16050 1/20 0.54
GFER P55789 1/20 0.54
NGLY1 Q96IV0 1/20 0.54
CXCR2 P25025 1/20 0.54
AKR1C3 P42330 5/20 0.53
AKR1C2 P52895 5/20 0.53
PTGS1 P23219 3/20 0.53
TAS2R14 Q9NYV8 2/20 0.53
PTGS2 P35354 2/20 0.53
FABP3 P05413 1/20 0.50
FABP5 Q01469 1/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
ALDH1A1 P00352 2/20 0.49
TEAD4 Q15561 1/20 0.49
TTR P02766 1/20 0.49
DHODH Q02127 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7813700 0.88 FABP4 (0.57) FABP4PBRM1MAPTALOX15GFER
SCHEMBL11797277 0.87 RHOA (0.55) FABP4PBRM1MAPTGFERNGLY1
SCHEMBL27427431 0.86 DHODH (0.54) FABP4PBRM1MAPTCXCR2AKR1C3
Butyl Alcohol SCHEMBL27704709 0.85 FABP4 (0.51) FABP4PBRM1MAPTALOX15GFER
Fenamic Acid SCHEMBL25828 0.84 FABP4 (0.92) FABP4PBRM1MAPTALOX15GFER
Fenamic Acid SCHEMBL29622832 0.84 FABP4 (0.92) FABP4PBRM1MAPTALOX15GFER
SCHEMBL3364062 0.84 FABP4 (0.66) FABP4MAPTALOX15GFERNGLY1
SCHEMBL1962364 0.82 POLB (0.53) FABP4PBRM1MAPTGFERNGLY1
SCHEMBL24620908 0.82 ALDH1A1 (0.50) FABP4PBRM1MAPTAKR1C3AKR1C2
SCHEMBL1962523 0.82 MEN1 (0.57) FABP4PBRM1MAPTALOX15AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104730196-A Crude polysaccharide detection method SUZHOU LONBO CALIBRATION AND TESTING CO LTD 2015-06-24 CN claimed
EP-0282322-B1 Novel serotonin inhibitors and pharmaceutical compositions containing them, and microbiological processes and organisms for the production thereof KYOWA HAKKO KOGYO KK (JP) 1994-06-22 EP claimed
EP-0372986-B1 COMPOUND KS-505 AND A PROCESS FOR PRODUCING THE SAME KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1993-03-24 EP claimed
EP-0255037-B1 A METHOD FOR FORMING POLYIMIDE FILM BY CHEMICAL VAPOR DEPOSITION HITACHI, LTD. (JP) 1992-12-09 EP claimed
EP-0282322-A2 Novel serotonin inhibitors and pharmaceutical compositions containing them, and microbiological processes and organisms for the production thereof KYOWA HAKKO KOGYO CO., LTD. (JP) 1988-09-14 EP claimed
US-4759958-A Method for forming polyimide film by chemical vapor deposition HITACHI, LTD. (JP) 1988-07-26 US claimed
EP-0255037-A2 A method for forming polyimide film by chemical vapor deposition HITACHI, LTD. (JP) 1988-02-03 EP claimed
JP-4112896-A None JP disclosed
JP-55108887-A None JP disclosed
JP-56039098-A None JP disclosed
JP-59011302-A None JP disclosed
CN-113336808-B Glycoside compound extracted and separated from lily, and method and application thereof 成都普思生物科技股份有限公司 2024-02-20 CN disclosed
CN-116678876-B Cosmetic ingredient detection device 烟台市食品药品检验检测中心(烟台市药品不良反应监测中心、烟台市粮油质量检测中心) 2023-10-10 CN disclosed
CN-86108686-A The production of anti-oxidizing compounds and purposes 1987-09-16 CN disclosed
EP-0228273-A2 Anti-oxidizing compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1987-07-08 EP disclosed
JP-S5911302-A ADLAY POLYSACCHARIDE SUBSTANCE AND LIPOMETABOLISM IMPROVER SNOW BRAND MILK PROD CO LTD 1984-01-20 JP disclosed
US-4423218-A Antibiotic neplanocin A TOYO JOZO KABUSHIKI KAISHA (JP) 1983-12-27 US disclosed
JP-S5639098-A NOVEL OLIGOSACCHARIDE AND ITS PREPARATION RIKAGAKU KENKYUSHO 1981-04-14 JP disclosed
JP-S55108887-A NOVEL OLIGO SACCHARIDE AND ITS PREPARATION RIKAGAKU KENKYUSHO 1980-08-21 JP disclosed
JP-S05639098-A 0001-01-01 JP disclosed