Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.63 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.63 |
| ▸ | DHFR | P00374 | 1/20 | 0.63 |
| ▸ | MPO | P05164 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963952 | 0.84 | FABP4 (0.68) | FABP4AKR1C3AKR1C2PTGS2MEN1 | |
| Fenamic Acid SCHEMBL27681709 | 0.83 | FABP4 (0.85) | FABP4AKR1C3AKR1C2PTGS2MEN1 | |
| Fenamic Acid SCHEMBL29622832 | 0.83 | FABP4 (0.92) | FABP4AKR1C3AKR1C2PTGS2MEN1 | |
| Fenamic Acid SCHEMBL25828 | 0.83 | FABP4 (0.92) | FABP4AKR1C3AKR1C2PTGS2MEN1 | |
| Fenamic Acid SCHEMBL27925717 | 0.81 | FABP4 (0.82) | FABP4AKR1C3AKR1C2PTGS2MEN1 | |
| Fenamic Acid SCHEMBL28520019 | 0.81 | FABP4 (0.89) | FABP4AKR1C3AKR1C2PTGS2MEN1 | |
| Fenamic Acid SCHEMBL10800939 | 0.81 | FABP4 (0.89) | FABP4AKR1C3AKR1C2PTGS2MEN1 | |
| Fenamic Acid SCHEMBL3657701 | 0.81 | FABP4 (0.89) | FABP4AKR1C3AKR1C2PTGS2MEN1 | |
| Fenamic Acid SCHEMBL27646881 | 0.81 | FABP4 (0.89) | FABP4AKR1C3AKR1C2PTGS2MEN1 | |
| Fenamic Acid SCHEMBL11800213 | 0.81 | FABP4 (0.89) | FABP4AKR1C3AKR1C2PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928880-B1 | PHENYLETHYLPYRIDINE DERIVATIVES AS PDE4-INHIBITORS AND MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-02-14 | — | — | EP | disclosed |
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | FABP4 3833/4885AKR1C3 510/4885AKR1C2 1252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.