Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | MMP16 | P51512 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL19639563 | 0.93 | LMNA (0.35) | TSHRALOX5MMP2MMP9MMP3 | |
| Acetic Acid SCHEMBL19639567 | 0.91 | TSHR (0.37) | TSHRALOX5KMT2AIRAK4PDCD1 | |
| Oxalic Acid SCHEMBL19639580 | 0.91 | TSHR (0.37) | TSHRALOX5MMP2MMP9MMP3 | |
| SCHEMBL19639527 | 0.91 | KMT2A (0.37) | TSHRALOX5KMT2AIRAK4PDCD1 | |
| SCHEMBL30500521 | 0.91 | KMT2A (0.37) | TSHRALOX5KMT2AIRAK4PDCD1 | |
| Methyl Alcohol SCHEMBL28857894 | 0.89 | KMT2A (0.36) | TSHRALOX5KMT2AIRAK4PDCD1 | |
| Maleic Acid SCHEMBL19639577 | 0.87 | HCAR2 (0.41) | TSHRALOX5IRAK4PDCD1CD274 | |
| Fumaric Acid SCHEMBL19639547 | 0.87 | HCAR2 (0.41) | TSHRALOX5IRAK4PDCD1CD274 | |
| Benzoic Acid SCHEMBL19639530 | 0.87 | TSHR (0.41) | TSHRALOX5KMT2APDCD1CD274 | |
| Sulfuric Acid SCHEMBL19639569 | 0.86 | ESR1 (0.36) | MMP2MMP9MMP3MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342026-A1 | ISOPROPOXY-PHENYLGUANIDINE SERIES SALT AND APPLICATION THEREOF IN PREPARING GROWTH PROMOTERS FOR ANIMAL FEED | Guangzhou Insighter Biotechnology Co., Ltd. (CN) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342026-A1 | ISOPROPOXY-PHENYLGUANIDINE SERIES SALT AND APPLICATION THEREOF IN PREPARING GROWTH PROMOTERS FOR ANIMAL FEED | SUCNR1, SORD, BPGM | TSHR 1815/4885ALOX5 2050/4885MMP2 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.