Sugi Predict

Sugi Predict / Compounds / SCHEMBL19640845

SCHEMBL19640845

SCHEMBL19640845

c1ccc(-c2ccc(-n3c4ccccc4c4c5c6ccccc6n(-c6nc7ccccc7nc6-c6ccccc6)c5ccc43)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 2/20 0.40
▸ CASP1 P29466 1/20 0.40
▸ HRH4 Q9H3N8 1/20 0.40
▸ DHODH Q02127 2/20 0.39
▸ KDM4E B2RXH2 6/20 0.39
▸ L3MBTL1 Q9Y468 3/20 0.39
▸ ATM Q13315 1/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ GAA P10253 2/20 0.39
▸ HPGD P15428 1/20 0.39
▸ MEN1 O00255 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ LMNA P02545 2/20 0.38
▸ TDP1 Q9NUW8 2/20 0.38
▸ HSP90AA1 P07900 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ ESR1 P03372 1/20 0.37
▸ ESR2 Q92731 1/20 0.37
▸ POLB P06746 1/20 0.36
▸ HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19653892 1.00 HSD17B10 (0.40) HSD17B10CASP1HRH4DHODHKDM4E
SCHEMBL19653879 0.97 KDM4E (0.42) HSD17B10CASP1HRH4DHODHKDM4E
SCHEMBL20152146 0.97 KDM4E (0.41) HSD17B10CASP1HRH4DHODHKDM4E
SCHEMBL19640843 0.95 KDM4E (0.45) HSD17B10CASP1HRH4KDM4EL3MBTL1
SCHEMBL20152135 0.95 HSD17B10 (0.43) HSD17B10CASP1HRH4DHODHKDM4E
SCHEMBL19653894 0.93 PIK3R1 (0.40) HSD17B10CASP1HRH4DHODHKDM4E
SCHEMBL19653896 0.93 PIK3R1 (0.40) HSD17B10CASP1HRH4DHODHKDM4E
SCHEMBL24596589 0.93 KDM4E (0.41) HSD17B10CASP1HRH4DHODHKDM4E
SCHEMBL24596716 0.93 KDM4E (0.41) HSD17B10CASP1HRH4DHODHKDM4E
SCHEMBL19655101 0.92 HSD17B10 (0.46) HSD17B10CASP1HRH4DHODHKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11800795-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-10-24 — — US disclosed
US-11800795-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-10-24 — — US disclosed
US-11711977-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 — — US disclosed
US-11711977-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 — — US disclosed
US-20230115134-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-04-13 — — US disclosed
US-20210193934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-24 — — US disclosed
US-10985328-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-20 — — US disclosed
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 — — US disclosed
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 — — US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 — — US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 — — US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 — — US disclosed
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 — — US disclosed
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10985328-B2 Organic electroluminescent materials and devices AZI2, INMT, PIR HSD17B10 3969/4885CASP1 3836/4885HRH4 2133/4885
US-11711977-B2 Organic electroluminescent materials and devices AZI2, INMT, PIR HSD17B10 3969/4885CASP1 3836/4885HRH4 2133/4885
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AZI2, INMT, PIR HSD17B10 3969/4885CASP1 3836/4885HRH4 2133/4885
US-20230115134-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF PIEZO1, ORAI2, OR10J3 HSD17B10 2684/4885CASP1 611/4885HRH4 4510/4885
US-11800795-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof PIEZO1, ORAI2, OCIAD1 HSD17B10 2507/4885CASP1 250/4885HRH4 4530/4885
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO HSD17B10 3487/4885CASP1 3467/4885HRH4 1559/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO HSD17B10 3487/4885CASP1 3467/4885HRH4 1559/4885
US-20210193934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AZI2, INMT, PIR HSD17B10 3969/4885CASP1 3836/4885HRH4 2133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.