Guanidine

Guanidine

SCHEMBL19644046

CCCl.N=C(N)N

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanidine SCHEMBL28861357 0.96
Lindane SCHEMBL14718451 0.87 NOS3 (0.35)
Thiourea SCHEMBL9175288 0.85
Guanidine SCHEMBL28137273 0.82
Guanidine SCHEMBL1933907 0.78
Guanidine SCHEMBL5531666 0.78
Guanidine SCHEMBL27509592 0.78
Butane SCHEMBL10941992 0.78
Ethyl Chloride SCHEMBL28638127 0.77
Guanidine SCHEMBL11800113 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3886823-A1 WOVEN, NONWOVEN, COTTON, NONWOVEN-COTTON BLENDED POLYETHYLENE AND POLIPROPILEN AND POLYSTYRENE MASK, WOUND DRESSING, PANTY, BRA, HANDKERCHIEF, PAD, SCOURING PAD, DISPOSABLE SURGICAL DRESS, DISPOSABLE SHEETS WITH ANTIMICROBIAL PROPERTIES UCAR Health GmbH (DE) 2021-10-06 EP disclosed
EP-3773502-A1 TREATMENT OF CANCER BY GUANIDINIUM DERIVATIVES UCAR Health GmbH (DE) 2021-02-17 EP disclosed
WO-2020112039-A1 WOVEN, NONWOVEN, COTTON, NONWOVEN-COTTON BLENDED POLYETHYLENE AND POLIPROPILEN AND POLYSTYRENE MASK, WOUND DRESSING, PANTY, BRA, HANDKERCHIEF, PAD, SCOURING PAD, DISPOSABLE SURGICAL DRESS, DISPOSABLE SHEETS WITH ANTIMICROBIAL PROPERTIES DILCEM KIMYA VE DENISMANLIK ITH. IHR. SAN. TIC. LTD. STI. (TR) 2020-06-04 WO disclosed
WO-2019194756-A1 TREATMENT OF CANCER BY GUANIDINIUM DERIVATIVES UCAR DILEK (TR) 2019-10-10 WO disclosed
WO-2017205828-A1 GUANIDINIUM-BASED IONIC LIQUIDS IN ABSORPTION CHILLERS YAZAKI CORPORATION (JP) 2017-11-30 WO disclosed