Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Testosterone Enanthate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR known ✓ | P10275 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 10/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.79 |
| ▸ | MAPT | P10636 | 6/20 | 0.79 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.79 |
| ▸ | PGR | P06401 | 5/20 | 0.79 |
| ▸ | TSHR | P16473 | 5/20 | 0.79 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.79 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.79 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.79 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17541886 | 1.00 | LMNA (1.00) | LMNACYP3A4MAPTNR3C1PGR | |
| Testosterone Undecanoate SCHEMBL5491530 | 1.00 | LMNA (1.00) | LMNACYP3A4MAPTNR3C1PGR | |
| Testosterone Undecanoate SCHEMBL17545317 | 1.00 | LMNA (1.00) | LMNACYP3A4MAPTNR3C1PGR | |
| SCHEMBL17541885 | 1.00 | LMNA (1.00) | LMNACYP3A4MAPTNR3C1PGR | |
| SCHEMBL11429123 | 1.00 | LMNA (1.00) | LMNACYP3A4MAPTNR3C1PGR | |
| SCHEMBL24555427 | 1.00 | LMNA (1.00) | LMNACYP3A4MAPTNR3C1PGR | |
| SCHEMBL17541905 | 1.00 | LMNA (1.00) | LMNACYP3A4MAPTNR3C1PGR | |
| SCHEMBL17537539 | 1.00 | LMNA (1.00) | LMNACYP3A4MAPTNR3C1PGR | |
| Testosterone Enanthate SCHEMBL22425430 | 1.00 | LMNA (1.00) | LMNACYP3A4MAPTNR3C1PGR | |
| Testosterone Enanthate SCHEMBL18437534 | 1.00 | LMNA (1.00) | LMNACYP3A4MAPTNR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180071390-A1 | COMPOSITIONS OF PHARMACEUTICAL ACTIVES CONTAINING DIETHYLENE GLYCOL MONOETHYL ETHER OR OTHER ALKYL DERIVATIVES | THEMIS MEDICARE LIMITED (IN) | 2018-03-15 | — | — | US | disclosed |
| US-9827315-B2 | Compositions of pharmaceutical actives containing diethylene glycol monoethyl ether or other alkyl derivatives | THEMIS MEDICARE LIMITED (IN) | 2017-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180071390-A1 | COMPOSITIONS OF PHARMACEUTICAL ACTIVES CONTAINING DIETHYLENE GLYCOL MONOETHYL ETHER OR OTHER ALKYL DERIVATIVES | DSG1, DEGS1, PLA2G2E | AR 719/4885LMNA 1490/4885CYP3A4 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.