Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968292 | 0.84 | KMT2A (0.50) | ENPP2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1671998 | 0.83 | KMT2A (0.56) | ENPP2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6593023 | 0.80 | FADS1 (0.67) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL1753321 | 0.79 | JAK2 (0.68) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL11857282 | 0.79 | JAK2 (0.56) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL11842224 | 0.79 | JAK2 (0.52) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5925259 | 0.79 | MAPT (0.59) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL15091807 | 0.78 | JAK2 (0.62) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL1726342 | 0.78 | ALDH1A1 (0.63) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL15361780 | 0.77 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |