Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964514 | 0.84 | ENPP2 (0.53) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL1725338 | 0.82 | ALDH1A1 (0.53) | KMT2AMEN1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL6594872 | 0.78 | P2RX1 (0.58) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL13086025 | 0.77 | ALDH1A1 (0.47) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2927223 | 0.77 | KMT2A (0.48) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL2931591 | 0.77 | HSD11B1 (0.54) | KMT2AMEN1MAPTPPARGLMNA | |
| SCHEMBL2927703 | 0.77 | NPC1 (0.60) | MAPK1RAB9ANPC1 | |
| SCHEMBL2927215 | 0.77 | HPGD (0.55) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL1455196 | 0.75 | KMT2A (0.73) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL18146208 | 0.74 | MDM2 (0.55) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |