Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22199660 | 0.95 | POLB (0.49) | POLBHPGDPKMHTTMEN1 | |
| SCHEMBL20374788 | 0.94 | POLB (0.46) | POLBHPGDPKMHTTMEN1 | |
| SCHEMBL23119558 | 0.92 | POLB (0.47) | POLBHPGDPKMHTTMEN1 | |
| SCHEMBL20340664 | 0.89 | POLB (0.47) | POLBHPGDPKMHTTMEN1 | |
| SCHEMBL18922367 | 0.83 | POLB (0.49) | POLBHPGDPKMHTTMEN1 | |
| SCHEMBL19200801 | 0.83 | L3MBTL1 (0.43) | POLBHPGDHTTLMNASMN1; SMN2 | |
| SCHEMBL19182655 | 0.82 | L3MBTL1 (0.48) | POLBHPGDHTTLMNASMN1; SMN2 | |
| SCHEMBL19200319 | 0.79 | TSHR (0.49) | POLBHPGDHTTLMNASMN1; SMN2 | |
| SCHEMBL21713229 | 0.78 | PKM (0.49) | POLBHPGDPKMHTTMEN1 | |
| SCHEMBL2718359 | 0.76 | L3MBTL1 (0.69) | POLBHTTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828378-B2 | Kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2017-11-28 | — | — | US | disclosed |