Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 14/20 | 0.54 |
| ▸ | CLK2 | P49760 | 13/20 | 0.54 |
| ▸ | CLK3 | P49761 | 13/20 | 0.54 |
| ▸ | WNT1 | P04628 | 6/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439285 | 0.92 | DYRK1A (0.55) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL19645545 | 0.91 | DYRK1A (0.55) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL20439281 | 0.90 | DYRK1A (0.54) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL20976060 | 0.90 | CLK2 (0.46) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17587781 | 0.89 | DYRK1A (0.60) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL19363336 | 0.88 | WNT1 (0.58) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL19645591 | 0.87 | DYRK1A (0.54) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL19645552 | 0.87 | CLK2 (0.49) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17587800 | 0.86 | WNT1 (0.59) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL19356527 | 0.85 | CLK2 (0.51) | DYRK1ACLK2CLK3WNT1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215753-A1 | 2-(1H-INDAZOL-3-YL)-1H-IMIDAZO[4,5-C]PYRIDINE AND THERAPEUTIC USES THEREOF | VICKERS VENTURE FUND VI (PLAN) PTE. LTD. (SG) | 2018-08-02 | — | — | US | disclosed |
| US-9828372-B2 | 2-(1H-indazol-3-yl)-1H-imidazo[4,5-C]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2017-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215753-A1 | 2-(1H-INDAZOL-3-YL)-1H-IMIDAZO[4,5-C]PYRIDINE AND THERAPEUTIC USES THEREOF | WNT1, WNT3, WNT3A | DYRK1A 735/4885CLK2 803/4885CLK3 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.