Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29107041 | 0.95 | TSHR (0.33) | ALDH1A1EPHX1LMNATSHR | |
| SCHEMBL13804589 | 0.89 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL13181417 | 0.87 | TSHR (0.40) | EPHX1TSHR | |
| SCHEMBL23371063 | 0.84 | EPHX1 (0.31) | EPHX1LMNATSHR | |
| SCHEMBL13181419 | 0.84 | TSHR (0.42) | EPHX1TSHR | |
| SCHEMBL22624028 | 0.84 | TSHR (0.42) | EPHX1TSHR | |
| SCHEMBL20413846 | 0.84 | TSHR (0.42) | EPHX1TSHR | |
| SCHEMBL24943233 | 0.84 | TSHR (0.42) | EPHX1TSHR | |
| SCHEMBL18430943 | 0.84 | TSHR (0.42) | EPHX1TSHR | |
| SCHEMBL21665296 | 0.80 | FDPS (0.35) | ALDH1A1EPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365605-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-11-16 | — | — | US | disclosed |
| US-20230225195-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
| US-9827248-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365605-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | SOST, SOS1, SOS2 | ALDH1A1 3594/4885EPHX1 1111/4885LMNA 3180/4885 |
| US-20230225195-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | H1-0, H1-2, H1-4 | ALDH1A1 157/4885EPHX1 20/4885LMNA 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.