SCHEMBL19646217

SCHEMBL19646217

Cc1cc(O)c(Cl)cc1OCc1c(Cl)cccc1-n1nnn(C)c1=O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 2/20 0.35
BDKRB2 P30411 8/20 0.34
MET P08581 1/20 0.34
MAPT P10636 1/20 0.32
NR1H4 Q96RI1 1/20 0.32
RORC P51449 1/20 0.32
RIPK1 Q13546 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19646233 0.94 SLC22A12 (0.35) MRGPRX4BDKRB2
SCHEMBL19646118 0.94 MRGPRX4 (0.35) MRGPRX4BDKRB2METMAPTNR1H4
SCHEMBL19646218 0.92 MRGPRX4 (0.35) MRGPRX4METRIPK1
SCHEMBL19646193 0.91 BDKRB2 (0.33) MRGPRX4BDKRB2
SCHEMBL19646189 0.91 MRGPRX4 (0.35) MRGPRX4BDKRB2
SCHEMBL19646115 0.91 MAPT (0.37) MRGPRX4BDKRB2MAPT
SCHEMBL19646168 0.91 BDKRB2 (0.34) MRGPRX4BDKRB2MAPT
SCHEMBL19646191 0.91 ADCYAP1R1 (0.35) BDKRB2MAPT
SCHEMBL16920809 0.91 BDKRB2 (0.35) MRGPRX4BDKRB2MAPTNR1H4
SCHEMBL18427414 0.91 BDKRB2 (0.31) MRGPRX4BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 US disclosed