SCHEMBL19646191

SCHEMBL19646191

COc1cccc(-n2nnn(C)c2=O)c1COc1cc(Cl)c(O)cc1C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADCYAP1R1 P41586 1/20 0.35
BDKRB2 P30411 9/20 0.34
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
DPP4 P27487 1/20 0.33
ATP4A P20648 1/20 0.33
ATP4B P51164 1/20 0.33
KCNB1 Q14721 1/20 0.32
IL6 P05231 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19646168 0.92 BDKRB2 (0.34) BDKRB2MAPTALDH1A1
SCHEMBL19646165 0.92 MRGPRX4 (0.36) ADCYAP1R1BDKRB2MAPTDPP4
SCHEMBL16920778 0.91 MEN1 (0.36) BDKRB2KDM4EMEN1ALDH1A1KMT2A
SCHEMBL19646233 0.91 SLC22A12 (0.35) BDKRB2
SCHEMBL19646217 0.91 MRGPRX4 (0.35) BDKRB2MAPT
SCHEMBL19646109 0.91 ATP4A (0.34) MAPTATP4AATP4BKCNB1IL6
SCHEMBL18427405 0.89 P2RX7 (0.33) BDKRB2
SCHEMBL18427431 0.89 RORC (0.34) BDKRB2
SCHEMBL19646114 0.89 MRGPRX4 (0.33) ADCYAP1R1MEN1KMT2AATP4AATP4B
SCHEMBL19646189 0.89 MRGPRX4 (0.35) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 US disclosed