Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | PLEC | Q15149 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 11/20 | 0.53 |
| ▸ | CA1 | P00915 | 9/20 | 0.53 |
| ▸ | CA2 | P00918 | 9/20 | 0.53 |
| ▸ | CA12 | O43570 | 5/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456349 | 0.88 | USP2 (0.62) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL19886589 | 0.86 | USP2 (0.62) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL12061907 | 0.85 | USP2 (0.66) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL12045940 | 0.84 | USP2 (0.68) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| 6-Carboxyfluorescein SCHEMBL9906208 | 0.83 | USP2 (0.69) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| 6-Carboxyfluorescein SCHEMBL29369299 | 0.83 | USP2 (0.69) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL13384808 | 0.82 | USP2 (0.85) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL17974475 | 0.82 | DNASE1L3 (0.68) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL13880697 | 0.82 | USP2 (0.62) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL18754815 | 0.82 | USP2 (0.62) | USP2L3MBTL1DNASE1L3PRMT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3670523-A1 | 5-METHOXY. 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | Agilent Technologies, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| EP-2755984-B1 | 5-METHOXY. 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | AGILENT TECHNOLOGIES INC (US) | 2020-02-12 | — | — | EP | disclosed |
| EP-2307565-B1 | REVERSIBLE NUCLEOSIDES AND NUCLEOTIDES TERMINATORS AND THEIR USE IN DNA SEQUENCING | LASERGEN INC (US) | 2017-11-29 | — | — | EP | disclosed |