SCHEMBL13880697

SCHEMBL13880697

CC(C)C(=O)c1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
DNASE1L3 Q13609 1/20 0.58
PRMT1 Q99873 1/20 0.58
MEN1 O00255 2/20 0.57
POLB P06746 2/20 0.57
KMT2A Q03164 2/20 0.57
ALPL P05186 1/20 0.57
ALPI P09923 1/20 0.57
ALPG P10696 1/20 0.57
ATM Q13315 1/20 0.55
PLEC Q15149 1/20 0.55
ALB P02768 1/20 0.51
CA9 Q16790 9/20 0.50
CA1 P00915 7/20 0.49
CA2 P00918 7/20 0.49
ESR1 P03372 1/20 0.48
CA12 O43570 2/20 0.47
HTRA2 O43464 1/20 0.46
HTRA1 Q92743 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19543669 0.93 USP2 (0.69) USP2L3MBTL1DNASE1L3PRMT1MEN1
6-Carboxyfluorescein SCHEMBL29369299 0.90 USP2 (0.69) USP2L3MBTL1DNASE1L3PRMT1MEN1
6-Carboxyfluorescein SCHEMBL9906208 0.90 USP2 (0.69) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL12061907 0.89 USP2 (0.66) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL13497987 0.87 USP2 (0.59) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL12604830 0.87 USP2 (0.69) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL14642481 0.86 USP2 (0.62) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL13785142 0.86 DNASE1L3 (0.63) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL13401323 0.86 USP2 (0.62) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL16231516 0.86 USP2 (0.64) USP2L3MBTL1DNASE1L3PRMT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230012304-A1 POLYMERIC TANDEM DYES WITH LINKER GROUPS Sony Group Corporation (JP) 2023-01-12 US disclosed
US-11312736-B1 Programmable polymeric drugs SONY CORPORATION (JP) 2022-04-26 US disclosed
US-10041115-B2 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing LASERGEN, INC. (US) 2018-08-07 US disclosed
US-20170327886-A1 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING LASERGEN, INC. (US) 2017-11-16 US disclosed
US-20090111100-A1 MINOR GROOVE BINDER - ENERGY TRANSFER OLIGONUCLEOTIDES AND METHODS FOR THEIR USE ELITECH HOLDING B.V. (NL) 2009-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11312736-B1 Programmable polymeric drugs NCL, PBRM1, LPXN USP2 2142/4885L3MBTL1 81/4885DNASE1L3 446/4885
US-20090111100-A1 MINOR GROOVE BINDER - ENERGY TRANSFER OLIGONUCLEOTIDES AND METHODS FOR THEIR USE SSBP1, SNRPE, TARBP1 USP2 4870/4885L3MBTL1 223/4885DNASE1L3 517/4885
US-10041115-B2 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing RNGTT, NT5C3B, NSUN2 USP2 1610/4885L3MBTL1 205/4885DNASE1L3 176/4885
US-20170327886-A1 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING RNGTT, NT5C3B, NSUN2 USP2 1587/4885L3MBTL1 196/4885DNASE1L3 170/4885
US-20230012304-A1 POLYMERIC TANDEM DYES WITH LINKER GROUPS CHRM1, MTCL3, TMT1A USP2 2719/4885L3MBTL1 22/4885DNASE1L3 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.