Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18409048 | 0.91 | AKR1C3 (0.57) | MAPTLMNAAKR1C3TSHRNR4A1 | |
| SCHEMBL12069726 | 0.91 | AKR1C3 (0.57) | MAPTLMNAAKR1C3TSHRNR4A1 | |
| SCHEMBL19648915 | 0.89 | CA2 (0.44) | MAPTLMNAAKR1C3ALDH1A1SMN1; SMN2 | |
| SCHEMBL17278976 | 0.87 | AKR1C3 (0.54) | MAPTLMNAAKR1C3TSHRNR4A1 | |
| SCHEMBL19844446 | 0.84 | AKR1C3 (0.50) | MAPTLMNAAKR1C3TSHRNR4A1 | |
| SCHEMBL2203983 | 0.82 | AKR1C3 (0.68) | MAPTLMNAAKR1C3TSHRNR4A1 | |
| SCHEMBL19648743 | 0.80 | MAPT (0.52) | MAPTLMNAAKR1C3TSHRNR4A1 | |
| SCHEMBL12071146 | 0.80 | AKR1C3 (0.47) | MAPTLMNAAKR1C3TSHRNR4A1 | |
| SCHEMBL17368563 | 0.79 | CA12 (0.47) | MAPTLMNAAKR1C3TSHRALDH1A1 | |
| SCHEMBL12069818 | 0.79 | CA12 (0.47) | MAPTLMNAAKR1C3TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580289-B1 | BLACK DICHROIC DYE | BASF SE (DE) | 2017-11-29 | — | — | EP | disclosed |