Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19648938 | 0.82 | MAPT (0.46) | MAPTLMNAALDH1A1GAANPC1 | |
| SCHEMBL19648735 | 0.80 | MAPT (0.52) | MAPTLMNATSHRNR4A1AKR1C3 | |
| SCHEMBL2203983 | 0.78 | AKR1C3 (0.68) | MAPTLMNATSHRNR4A1AKR1C3 | |
| SCHEMBL19648817 | 0.76 | CA2 (0.51) | MAPTLMNAAKR1C3ALDH1A1GAA | |
| SCHEMBL19648933 | 0.74 | KIF11 (0.40) | MAPTTSHRALDH1A1GAARAB9A | |
| SCHEMBL3994030 | 0.73 | EPHX2 (0.70) | MAPTLMNAAKR1C3ALDH1A1GAA | |
| SCHEMBL12071146 | 0.72 | AKR1C3 (0.47) | MAPTLMNATSHRNR4A1AKR1C3 | |
| SCHEMBL22169111 | 0.72 | ALDH1A1 (0.64) | MAPTLMNATSHRALDH1A1GAA | |
| SCHEMBL19648924 | 0.71 | LGMN (0.53) | MAPTLMNAALDH1A1GAANPC1 | |
| SCHEMBL23059781 | 0.70 | AKR1C3 (0.57) | MAPTLMNATSHRNR4A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580289-B1 | BLACK DICHROIC DYE | BASF SE (DE) | 2017-11-29 | — | — | EP | disclosed |