SCHEMBL1965008

SCHEMBL1965008

CCOC(=O)c1ccc2[nH]cnc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
ATM Q13315 2/20 0.53
HCRTR1 O43613 2/20 0.52
ALDH1A1 P00352 3/20 0.52
MEN1 O00255 3/20 0.52
HPGD P15428 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TP53 P04637 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
KDM4E B2RXH2 3/20 0.51
RAB9A P51151 3/20 0.51
MAPT P10636 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
POLB P06746 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1965011 0.88 KMT2A (0.65) KMT2AATMALDH1A1HPGDKDM4E
SCHEMBL30447626 0.88 KMT2A (0.65) KMT2AATMALDH1A1HPGDKDM4E
SCHEMBL9178130 0.86 LMNA (0.52) KMT2AALDH1A1MEN1HPGDL3MBTL1
SCHEMBL4265469 0.86 KMT2A (0.47) KMT2AATMHCRTR1ALDH1A1MEN1
SCHEMBL4265466 0.86 KMT2A (0.47) KMT2AATMHCRTR1ALDH1A1MEN1
SCHEMBL27799227 0.85 NPC1 (0.50) ALDH1A1HPGDKDM4ERAB9AMAPT
SCHEMBL6016890 0.84 CTNNB1 (0.44) KMT2AATMHCRTR1ALDH1A1MEN1
SCHEMBL6017091 0.84 HDAC6 (0.41) KMT2AATMHCRTR1ALDH1A1MEN1
SCHEMBL1378326 0.84 KMT2A (0.43) KMT2AATMHCRTR1ALDH1A1MEN1
SCHEMBL2353748 0.84 DGAT1 (0.49) KMT2AATMALDH1A1MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105521784-B A kind of TiO2Anode surface load C o3O4Method 哈尔滨工业大学 2017-11-03 CN claimed
CN-105506666-B A kind of decomposition water device 哈尔滨工业大学 2017-08-25 CN claimed
CN-118401531-A Benzimidazole compound and medical application thereof 中国科学院上海药物研究所 2024-07-26 CN disclosed
CN-115551862-B Macrocyclic inhibitors of peptidyl arginine deiminase 吉利德科学公司 2024-04-12 CN disclosed
CN-117279905-A Carboxy-benzimidazole GLP-1R modulating compounds 吉利德科学公司 2023-12-22 CN disclosed
CN-116444544-A Benzimidazole compound and medical application thereof 中国科学院上海药物研究所 2023-07-18 CN disclosed
WO-2023131333-A1 BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF 中国科学院上海药物研究所 2023-07-13 WO disclosed
CN-113227068-B GLP-1R agonists and uses thereof 上海齐鲁锐格医药研发有限公司 2023-06-13 CN disclosed
CN-115551862-A Macrocyclic inhibitors of peptidyl arginine deiminase 吉利德科学公司 2022-12-30 CN disclosed
WO-2022242696-A1 ARGININE METHYLTRANSFERASE INHIBITOR AND USE THEREOF 上海赛岚生物科技有限公司 2022-11-24 WO disclosed
WO-2022228490-A1 POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2022-11-03 WO disclosed
US-5153116-A Using a isothiazol-3-one or 1,2-benzoisothiazol-3-one compound in a layer also containing a spectral sensitizing dye; monochromatic films; negatives KONICA CORPORATION (JP) 1992-10-06 US disclosed
US-5053408-A Cardiovascular disorders KYOWA HAKKO KOGYO CO., LTD. (JP) 1991-10-01 US disclosed
EP-0393574-A2 Hexitol derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 1990-10-24 EP disclosed
EP-0367243-A1 A silver halide photographic light-sensitive material excellent in antistatic property KONICA CORPORATION (JP) 1990-05-09 EP disclosed
US-4917997-A MIXED WITH ASCORBIC ACID COMPONENT, SENSITIZING DYE, BISAMINOSTILBENE WITH PYRIMIDINE SUBSTITUTION FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
US-4550118-A ANTIULCER, ANTISECRETORY AGENT, HISTAMINE ANTAGONIST IKEDA MOHANDO CO., LTD. (JP) 1985-10-29 US disclosed
EP-0111685-A1 Benzazoles as histamine H2 receptor antagonists Ikeda Mohando Co., Ltd. (JP) 1984-06-27 EP disclosed
US-3986878-A SILVER HALIDE PHOTOGRAPHIC EMULSION FUJI PHOTO FILM CO., LTD. (JA) 1976-10-19 US disclosed
US-3985563-A Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-10-12 US disclosed